Resveratrol is a natural molecule that:
Reduces gene expression of inflammatory mediators
Relieves soreness · Speeds recovery
Metabarol · Equithrive Flex · Equithrive RSV · Equithrive Joint · Equithrive Performance
Petthrive Soft Chews for Dogs · Petthrive Soft Chews for Large Dogs


Metabarol™ is a premium scientific formula of our proprietary micro-encapsulated resveratrol (Resverasyn®) that is administered daily to support optimum metabolic function in horses. University conducted research demonstrated that Metabarol reduced insulin levels by an average of 30% after 45 days of administration in horses previously diagnosed with Equine Metabolic Syndrome via the oral glucose challenge test.
Active Ingredient: Resverayn® (Micro-Encapsulated Resveratrol) 4,000mg per daily dose
Inactive Ingredients: Saccharomyces Cerevisiae 1026, Natural Molasses Flavor and Diatomaceous Earth
Directions for Use: Administer 4 heaping scoops (30 grams on a daily basis) for best results divide recommended daily dosage between a.m. & p.m.
How it Works
Improves Metabolic Efficiency
Daily resveratrol administration improves energy metabolism through its effects on mitochondria, the body’s cellular powerhouse. Resveratrol activates an enzyme called Sirtuin 1 that causes mitochondria to more efficiently metabolize glucose. The result is increased energy output from cellular metabolic reactions.
Reduces Chronic Inflammation
Chronic inflammation decreases the sensitivity of insulin receptors to insulin, a condition referred to as insulin resistance (IR). Glucose is not readily transported into cells in animals with insulin resistance. To compensate for insulin resistance, the pancreas of IR animals typically produces and secretes larger amounts of insulin to promote entry of glucose into cells. The high levels of blood insulin associated with insulin resistance is a condition known as hyperinsulinemia, which can contribute to increased risk of laminitis, a devastating inflammatory condition of the hoof.
Daily Metabarol administration has been shown to decrease circulating levels of the pro-inflammatory mediator TNF-alpha in horses. The reduction in chronic inflammation associated with daily Metabarol administration improves insulin sensitivity in horses previously diagnosed with Equine Metabolic Syndrome. This improvement in insulin sensitivity explains the reduction in blood insulin levels in EMS horses exposed to the oral glucose challenge test after 45 days of Metabarol administration.
What is Equine Metabolic Syndrome?
Equine Metabolic Syndrome (EMS) is an endocrine disorder that affects a variety of horse breeds. EMS is characterized by insulin resistance (IR) and is diagnosed by elevated basal fasting insulin levels and/or an abnormal response to an oral sugar test or intravenous glucose challenge test.
Obese or overweight horses are particularly susceptible to developing EMS, although EMS can also occur in animals with a healthy or normal body weight. Horses with EMS frequently have a predisposition for the development of laminitis. Laminitis results from reduced blood flow and chronic inflammation in the laminae that connect the coffin bone to the hoof wall. Failure to properly manage insulin resistance in EMS horses, predisposed to laminitis, can lead to a life-threatening situation.

Equithrive Flex is a unique resveratrol-based formula that supports healthy joint function in your horse. Resveratrol reduces gene expression of inflammatory mediators to allow your horse to move comfortably during aging, training and competition. This product also contains therapeutic doses of compounds that support connective tissue health, specifically glucosamine, chondroitin and hyaluronic acid. Equithrive Flex is a stand alone product that does not require co-administration of any other nutraceuticals or supplements to support soundness and continued joint health in your horse.
Equithrive Flex contains our proprietary microencapsulated resveratrol ingredient Resverasyn™. Microencapsulation ensures resveratrol is absorbed in the gastrointestinal tract and transported throughout the body to reduce the production of inflammatory mediators. When not microencapsulated, resveratrol is rapidly metabolized and excreted before the compound can reach tissues and exert its effects in your horse.
Equithrive Flex is a molasses-flavored, powdered product that can be administered with a horse's daily feed ration.
| Dose | Reseverasyn | D-Glucosamine Sulfate |
Chondroitin Sulfate |
Hyaluronic Acid |
|
|---|---|---|---|---|---|
| Loading | 4 Scoops | 1000 milligrams | 7200 milligrams | 2400 milligrams | 200 milligrams |
| Maintenance | 2 Scoops | 500 milligrams | 3600 milligrams | 1200 milligrams | 100 milligrams |
Ingredients: Saccharomyces Cerevisiae 1026, D-Glucosamine Sulfate, Chondroitin Sulfate, Resverasyn (microencapsulated resveratrol), natural molasses flavoring and sodium hyaluronate.
| Equithrive Flex | Doses per Container | Cost per Day* |
|---|---|---|
| 2lb-Container | 60 | $2.33 |
| 8lb-Container | 240 | $2.00 |
*Note: cost per day is calculated on maintenance dosing of 2 scoops per day.


Equithrive RSV is a resveratrol paste product that supports healthy joint function in your horse. Resveratrol reduces gene expression of inflammatory mediators to allow your horse to move comfortably during aging, training and competition. Equithrive RSV contains our proprietary microencapsulated resveratrol ingredient Resverasyn™. Microencapsulation ensures resveratrol is absorbed in the gastrointestinal tract and transported throughout the body to reduce the production of inflammatory mediators. When not microencapsulated, resveratrol is rapidly metabolized and excreted before the compound can reach tissues and exert its effects in your horse.
| Equithrive RSV Dose | Resverasyn |
Doses per 60 cc syringe |
Cost per Dose |
|---|---|---|---|
| 10 mL | 2000 mg | 12 | $2.50 |
| 20 mL | 4000 mg | 6 | $5.00 |
Active Ingredient: Resverasyn (microencapsulated resveratrol) (200 mg of Resverasyn per cc of Equithrive RSV)
Inactive Ingredients: water, xantham gum, stevioside, natural apple flavor, sodium benzoate, citric acid


Equithrive Joint is a unique resveratrol-based formula that supports healthy joint function in your horse. Resveratrol reduces gene expression of inflammatory mediators to allow your horse to move comfortably during aging, training and competition. Equithrive Joint was released in 2009 and is the true pioneer product in equine resveratrol therapy. Researchers at the Gluck Equine Research Center have evaluated this product and verified that daily administration of Equithrive Joint produces a statistically significant reduction in circulating levels of inflammatory mediators.
Equithrive Joint contains our proprietary microencapsulated resveratrol product Resverasyn™. Microencapsulation ensures resveratrol is absorbed in the gastrointestinal tract and transported throughout the body to reduce the production of inflammatory mediators. When not microencapsulated, resveratrol is rapidly metabolized and excreted before the compound can reach tissues and exert its effects in your horse. Equithrive Joint also contains hyaluronic acid, the primary component of joint-lubricating synovial fluid and cartilage. Supplementation with hyaluronic acid may prevent the concentration of this compound from diminishing in synovial fluid and connective tissues during the natural aging process.
Equithrive Joint is a stand alone product that does not require co-administration of any other nutraceuticals or supplements to support soundness and continued joint health in your horse. Equithrive Joint is a powdered product that can be administered with a horse's daily feed ration.
| Dose | Resverasyn | Hyaluronic Acid |
||
|---|---|---|---|---|
| Loading | 4 scoops | 2000 mg |
200 mg | |
| Intensive Support | 4 scoops | 2000 mg |
200 mg | |
| Maintenance | 2 scoops | 1000 mg |
100 mg |
Ingredients: Grape Skin and Seed Powder, Fermentation Solubles, Saccharomyces Cerevisiae 1026, Resverasyn™ (Microencapsulated Resveratrol), Diatomaceous Earth and Sodium Hyaluronate.
| Equithrive Joint | Doses per Container* |
Cost per Day* |
|---|---|---|
| 1-lb Container | 30 | $2.33 |
| 2-lb Container | 60 | $2.17 |
| 8-lb Container | 240 | $2.00 |
*Note: cost per day and doses per container are calculated on maintenance dosing of 2 scoops per day.


Equithrive Performance is a pre-competition product that increases energy and stamina levels in your horse. This product contains an active ingredient called pterostilbene that supports peak muscle performance in horses. Equithrive Performance is the only equine product manufactured with Pterosyn™, our proprietary microencapsulated pterostilbene ingredient. Microencapsulation ensures pterostilbene is absorbed in the gastrointestinal tract and transported to muscle tissue, where it optimizes the efficiency of cellular metabolic reactions. When not microencapsulated, pterostilbene is rapidly metabolized and excreted before the compound can reach muscle tissue and exert its effect in your horse. Use Equithrive Performance with Pterosyn before your next competition to see your horse perform at its best!
Directions for Use: Administer 5 to 10 mL per 500 kg of body weight on each of the five days prior to competition and the day of competition. For best results divide recommended daily dosage between AM and PM.
| Equithrive Performance Dose | Pterosyn |
Doses per 60 cc syringe |
Cost per Dose |
|---|---|---|---|
| 5 mL | 1000 mg | 12 | $5.00 |
| 10 mL | 2000 mg | 6 | $10.00 |
Active Ingredient: Pterosyn (microencapsulated pterostilbene)(200 mg of Pterosyn per cc of Equithrive Performance)
Inactive Ingredients: water, xantham gum, stevioside, natural apple flavor, sodium benzoate, citric acid